Mutation frequencies in a birth–death branching process
نویسندگان
چکیده
منابع مشابه
Mutation frequencies in a birth-death branching process
First, we revisit a classic two-type branching process which describes cell proliferation and mutation; widespread application has been seen in cancer and microbial modelling. As the mutation rate tends to zero and the population size to infinity, the mutation times converge to a Poisson process. This yields the number of mutants and clone sizes. Other limits and exact results are also explored...
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ژورنال
عنوان ژورنال: The Annals of Applied Probability
سال: 2018
ISSN: 1050-5164
DOI: 10.1214/18-aap1413